Interested in dedicating a day to science? Happy to help us out with an experiment? Then you can be our next volunteer!
We have started combining breath and dried blood spot sampling to detect and quantify pseudoephedrine from the first volunteers, but we are looking for some more healthy volunteers. Especially healthy female volunteers appear difficult to find at the University of Leicester.
What’s the experiment? It’s a combination of taking breath samples (Sofia) and 10ul blood samples by finger pricking (Thalassa) after taking 2 tablets for a cold (2x60mg Sudafed).
What exactly? At the start you will have to breath out 5x for 30secs in a mount piece and your finger will be pricked with a sterile auto lancet to collect 3x 10ul of blood. You will then be asked to take the tablets and after half an hour the breath and blood collection will be repeated (breath will be reduced to 3x 30 sec from then onwards). The same will be repeated after 1h, 1.5, 2, 4, 4.5, 5, 6 hours of taking the tablets.
How long will it take? It will take 6 hours in total and you can come at the same time. The combination of breath and blood measurements only take 5 mins each person per time point so there is a lot of spare time (25 min per half an hour) plus a 2 hour (lunch) break between the 2h and 4h time point. There’s eduroam at the hospital so you could bring a laptop and work, read etc in the waiting time.
When? Let us know if you’re interested and we’ll find a date together.
Where? At the new DDU at Leicester Royal Infirmary.
Is there any scientific information available? We’ve got an information sheet for both breath and blood for you to read and a consent form to sign. The goal of both our experiments is to detect pseudoephedrine in the samples (it’s a higher dose than normally taken at once for having a cold, but lower than the daily maximum dose and/or doping or hallugenic doses).
Any restrictions? Unfortunately you can’t donate if you have a medical condition such as diabetes or hypertension, which needs regular medication. You also can’t have any other medication (such as paracetamol) neither a beer 24h prior to the sampling. So if you’re healthy and studying or working at the University of Leicester, you’re probably the person we are looking for J
Please let us know if you’ve got any questions or if you’re interested!
Sofia and Thalassa